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Ventricle-Brain Ratio on Computed Tomographic Scans

V. M. Synek, MD
Arch Gen Psychiatry. 1984;41(2):210-211. doi:10.1001/archpsyc.1984.01790130106015.
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To the Editor.—  During the past five years a number of articles dealing with ventricle-brain ratio (VBR) have been published in the Archives and other psychiatric journals. The VBR was first described and defined by my colleagues and I1,2 and elaborated further in my thesis,3 wherein I outlined the advantages and disadvantages of this ratio. I have also expressed my hope that the VBR will be replaced by automatic techniques that will not only evaluate the ventricle size but also take into account the subarachnoid spaces missed by this ratio. While I was introducing the VBR as a technique I met the criticism of a leading neuroradiologist, and it was not easy to get the ratio established as a routine technique. However, the ratio, as I presented it originally, is still widely used in the differentiation of subtypes in schizophrenia, manic depressive illness, drug addiction, dialysis encephalopathy, alcoholic

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