0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Differences in Diazepam and Oxazepam-Reply

Carl Salzman, MD; David Greenblatt, MD
Arch Gen Psychiatry. 1984;41(3):311. doi:10.1001/archpsyc.1984.01790140101018.
Text Size: A A A
Published online

ABSTRACT

In Reply.—  Inspection of the figures in our article shows that both groups of subjects were essentially at steady state at the end of two weeks of chronic drug administration. At this point, sedation for both drugs was approximately equivalent. As noted by DeVane and Stewart, the primary point of our study was to demonstrate the large differences between oxazepam and diazepam, not only in kinetic characteristics, but in clinical effect. We agree that the medical community needs to understand the use of long- v short-acting benzodiazepines, particularly in elderly patients.We would like to take this opportunity to comment also on terminology. Desmethyldiazepam in our article was referred to as nordazepam, yet general usage and our preference is to continue to use the term desmethyldiazepam to describe the primary demethylated active metabolite of diazepam as well as other long-acting benzodiazepines.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();