Article |

Selection of Neuroleptic Dosage

Martin H. Teicher, MD, PhD; Ross J. Baldessarini, MD
Arch Gen Psychiatry. 1985;42(6):636-637. doi:10.1001/archpsyc.1985.01790290118019.
Text Size: A A A
Published online

To the Editor.—  There continues to be a lack of quantitative data to guide the selection of appropriate doses of neuroleptic agents. Such information would be particularly useful for longterm treatment of chronically psychotic patients to minimize the risk ofDose-Effect Relationship for Fluphenazine Decanoate in the Treatment of Schizophrenia for One Year Study, yr Dosage Mean No. of Range, Dosage, Relapse Dropout Success Subjects mg/2 wk mg/2 wk* Rate, %† Rate, %‡ Rate, %§ Hogarty et al, 1 1979 55 12.5-125 41 35.1 Marder et al, 2 1984 22 25-50 36 20.2 22.7 62 Rifkin et al, 3 1977 19 12.5-50 31 5.3 42.1 53 Kane et al, 4,5 1983, 1984 64 12.5-50 31 7.0 Marder et al, 2 1984 28 5-10 22.4 7.1 72 Kane et al, 5 1984 36 2.5-10 20.0 Kane et al, 4, 5 1983, 1984 62 1.25-5 56.0 Hogarty et al, 6 1976 41 67.4 4.7 32 Rifkin et al, 3 1977 19


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview





Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.