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Stimulant Therapy of 'Adult Hyperactivity'-Reply

Jeffrey A. Mattes, MD
Arch Gen Psychiatry. 1985;42(8):840. doi:10.1001/archpsyc.1985.01790310108019.
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In Reply.—  I agree with Wender et al, as they have continued to find beneficial effects of stimulants in adults with ADD, that further work in this area is indicated, and that such work should use their inclusion criteria, if possible. The article by Wood et al1 was the impetus for our work; the emphasis by Wender et al2 on the PRS, and the current Utah criteria excluding certain diagnoses, were not available until after our study was under way.Hopefully, a stimulant-responsive subgroup of adults with ADD can be identified; however, as indicated by our article, it seems fair to say that stimulant response in adults with ADD is not as consistent as in children with ADD. The emphasis on the PRS seems arbitrary; one would expect the crucial factor to be the certainty of the childhood diagnosis. For example, a history of a diagnosis of ADD (or hyperactivity)

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