We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Blood Gas Changes and Hypophosphatemia in Lactate-Induced Panic

Christopher Bass, MD, MRCPsych; W. N. Gardner, DPhil, MRCP
Arch Gen Psychiatry. 1988;45(1):95-96. doi:10.1001/archpsyc.1988.01800250111014.
Text Size: A A A
Published online


To the Editor.—  Gorman et al1 urge that further work be aimed at defining the nature of ventilatory abnormalities in patients with panic disorder (PD) but do not elaborate on the substantial body of work that has already been published in this field. The important association between agoraphobia and hyperventilation (HV)-related complaints has already been established in different populations,2,3 and we have shown that some patients with agoraphobia and PD spend large portions of the waking day in the hypocapnic range (carbon dioxide partial pressure [Pco2], <30 mm Hg).4,5 For those patients at or close to the threshold for hypocapnia, relatively minor stressors, such as exercise, talking, or even exposure to phobic talk,6 may provoke sudden reductions in Pco2 that are accompanied by somatic symptoms and panic anxiety. Rapee7 also demonstrated that patients with PD had not only lower resting end-tidal Pco2 and


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.