0
Article |

Comment

Gerald L. Klerman, MD
Arch Gen Psychiatry. 1990;47(7):686-688. doi:10.1001/archpsyc.1990.01810190086015.
Text Size: A A A
Published online

To the Editor.—  At the Chief Editor's request, I will comment on the recent publication of the results of the NIMH Treatment of Depression Collaborative Research Program by Elkin et al and on Dr Klein's letter.Dr Klein raised a number of criticisms about the appropriate statistical techniques and the interpretation of the results. These criticisms merit attention but the issues should be viewed in the larger context of the study and its achievements.

Achievements.—  This is the largest psychotherapy research project ever undertaken in the United States, involving three collaborating field centers. It has the imprimatur of NIMH. Although multicenter trials are now common in clinical psychopharmacology, they have not been widely applied to evaluating psychotherapy. As such, the demonstration of the feasibility of designing and conducting this trial should be considered an achievement in itself.Moreover, the study pioneered a number of methods that have become the

Topics

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();