0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Nicotine Use as a Possible Risk Factor for Subcortical Abnormalities

Richard S. Epstein, MD
Arch Gen Psychiatry. 1990;47(12):1172. doi:10.1001/archpsyc.1990.01810240092015.
Text Size: A A A
Published online

To the Editor.—  The findings of Dupont et al1 contribute to the efforts to understand the structural and neuropsy-chological correlates of affective disorder.The authors note that the subcortical signal hyperintensities in the magnetic resonance imaging scans of a subgroup of bipolar patients might also be found in patients with multiple sclerosis or Binswanger's disease. They did not feel that this was relevant in their study because the magnetic resonance imaging abnormalities were not found in similarly screened agematched controls. While these patients were screened for alcohol and drug abuse, no mention was made of nicotine use. Roman2 reviewed the white matter lesions in dementia of the Binswanger type and noted that smoking may be one of the risk factors leading to diminished blood flow in susceptible subcortical regions. If there was a differential use of nicotine between subjects with positive or negative scans in the

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

Correspondence

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Submit a Comment

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();