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Subjective Conclusions About Schizophrenia-Reply

Arch Gen Psychiatry. 1992;49(1):74-75. doi:10.1001/archpsyc.1992.01820010074010.
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In Reply.—  We appreciate Puryear and colleagues' interest in our recent article.1 They apparently do not find fault with the methods used Or data contained in our report. Rather, they believe our interpretations of the data were inaccurate, which, they suggest, may lead to "unduly pessimistic" conclusions about the long-term outcome of schizophrenia. They specifically point to our phasic model of course of illness, indicating that the figure reflects a more negative course than does our discussion of themodel.Our phasic model represents a synthesis of several previously published outcome studies. There were vast differences in the methods used in these studies, so it was impossible to use a single outcome measure, such as Global Assessment Scale or Levels ofFunctioning scores, to synthesize the data. Thus, we believe it would have been misleading to "score" the y axis in our figure. Our phasic model was developed as an attempt to


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