We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

The Definition of Remission and Its Impact on the Length of a Depressive Episode-Reply

Ellen Frank, PhD; David J. Kupfer, MD
Arch Gen Psychiatry. 1993;50(5):408. doi:10.1001/archpsyc.1993.01820170094014.
Text Size: A A A
Published online


We applaud the effort of Drs Philipp and Fickinger that clearly underscores the point made in our report: varying definitions of response or remission will lead to quite different lengths of episode and illness-free periods. The careful follow-up study of 66 psychiatric inpatients described above clearly demonstrates that an episode can be anywhere from 1 to more than 6 months in length depending on the particular criteria set for defining remission. We concur that a broad consensus on operational definitions of change points would lead to a more interpretable literature on depressive illness. We look forward to seeing the authors' demonstration that the cutoff 3/4 leads to the most valid definition of remission, since the validity of various cutoffs must be established before consensus definitions can be promulgated appropriately.

Supported in part by a grant from the John D. and Catherine T. MacArthur Foundation Research Network on the Psychobiology of


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.