In 1990, the National Institute of Mental Health embarked on the National Plan for Research on Child and Adolescent Mental Disorders, a widely heralded program to capitalize on opportunities to better understand the causes of these disorders and to enhance prevention and treatment efforts. Leckman et al (page 715), assessing the plan's impact at the midpoint of its implementation, found that the climate for child-related research has improved, but financial support for such research has fallen far short of that recommended in the plan. They conclude that both clinicians and the general public have much to gain from full implementation of the plan. Four commentaries discuss this update.
Patients been reported to have global, diffuse brain structure abnormalities. In a meta-analysis, Elkis et al (page 735) conclude that groups of patients with depression also have these brain abnormalities, but the size of the effect is smaller than that