We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Article |

Is Research in Normal and Ill Children Involving Radiation Exposure Ethical?-Reply

B. J. Casey, PhD; Jonathan D. Cohen, MD, PhD
Arch Gen Psychiatry. 1996;53(11):1059-1060. doi:10.1001/archpsyc.1996.01830110097014.
Text Size: A A A
Published online


In Reply  The letter by Dr Morton, addresses a concern to us all—the safety and well-being of human subjects in research studies, and in particular healthy pediatric populations. Zametkin and colleagues1 present a PET study of adolescents with ADHD and matched normal controls. That study was an attempt to further understand brain systems underlying a disorder that affects a significant number of children each year. The exposure of these minors to radiation was held to minimal levels. Given that ADHD is a significant and important psychiatric disorder to study, afflicting thousands of children each year, this study seemed warranted.Nevertheless, we share Dr Morton's concerns about the use of any invasive procedure in pediatric populations. In this regard, we are encouraged by the fact that an alternative, noninvasive approach to functional neuroimaging in developmental populations is now available. This is functional magnetic resonance imaging (fMRI), which can be used to


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview





Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.