0
Article |

Retrograde Amnesia and Bilateral Electroconvulsive Therapy: Title and subTitle BreakLong-term Follow-up

Larry R. Squire, PhD; Pamela C. Slater; Patricia L. Miller
[+] Author Affiliations

Accepted for publication Aug 20, 1979.

Reprint requests to Veterans Administration Medical Center, 3350 La Jolla Village Dr, San Diego, CA 92161 (Dr Squire).


Arch Gen Psychiatry. 1981;38(1):89-95. doi:10.1001/archpsyc.1981.01780260091010
Text Size: A A A
Published online

• Memory for past events was assessed in 43 patients who had been prescribed bilateral electroconvulsive therapy (ECT) for relief of depressive illness. Four memory tests of personal or public events were administered before ECT, shortly after the fifth treatment, one week after completion of treatment, and about seven months later. The results indicated that ECT can initially disrupt recall of events that occurred many years previously, but recovery of these memories was virtually complete by seven months after treatment. It was also clear that persisting memory loss for information acquired only a few days before treatment can occur. For information acquired one to two years prior to treatment, recovery was substantial, but the results suggested that some memory problems might persist for events that occurred during this time period.

REFERENCES

Ilaria R, Prange AJ:  Convulsive therapy and other biological treatments , in Flack FF, Draghi SC (eds): The Nature and Treatment of Depression . New York, John Wiley & Sons Inc, 1975;, pp 271-308.
Turek IS, Hanlon TF:  The effectiveness and safety of electroconvulsive therapy (ECT) . J Nerv Ment Dis 164:419-431, 1977;.
Squire LR:  Electroconvulsive therapy and memory loss . Am J Psychiatry 134:997-1001, 1977;.
Harper RG, Wiens AN:  Electroconvulsive therapy and memory . J Nerv Ment Dis 161:245-254, 1975;.
Squire LR: Memory dysfunction and memory complaint: Long-term follow-up studies, in Autry J, Squire L, Cole J, et al (eds): ECT: Impact and Efficacy. New York, Spectrum Publications Inc, to be published.
Harper R: Anterograde amnesia: Acute effects of an average number of treatments, in Autry J, Squire L, Cole J, et al (eds): ECT: Impact and Efficacy. New York, Spectrum Publications Inc, to be published.
Squire LR, Slater PC:  Bilateral and unilateral ECT: Effects on verbal and nonverbal memory . Am J Psychiatry 135:1316-1320, 1978;.
Squire LR, Miller PL:  Diminution in anterograde amnesia following electroconvulsive therapy . Br J Psychiatry 125:490-495, 1974;.
Brunschwig L, Strain J, Bidder TG:  Issues in the assessment of post-ECT memory changes . Br J Psychiatry 119:73-74, 1971;.
Squire LR:  A stable impairment in remote memory following electroconvulsive therapy . Neuropsychologia 13:51-58, 1975;.
Bidder TG, Strain J, Brunschwig L:  Bilateral and unilateral ECT: Follow-up study and critique . Am J Psychiatry 127:737-745, 1970;.
Halliday AM, Davison K, Browne MW, et al:  A comparison of the effects on depression and memory of bilateral ECT and unilateral ECT to the dominant and nondominant hemispheres . Br J Psychiatry 114:997-1012, 1968;.
Squire LR, Chace PM:  Memory functions six to nine months after electroconvulsive therapy . Arch Gen Psychiatry 32:1557-1564, 1975;.
Russell WR, Nathan PW:  Traumatic amnesia . Brain 69:280-300, 1946;.
Squire LR, Slater PC, Chace PM:  Retrograde amnesia: Temporal gradient in very long-term memory following electroconvulsive therapy . Science 187:77-79, 1975;.
Squire LR, Chace PM, Slater PC:  Retrograde amnesia following electroconvulsive therapy . Nature 260:775-777, 1976;.
Squire LR, Cohen N:  Memory and amnesia: Resistance to disruption develops for years after learning . Behav Neural Biol 25:115-125, 1979;.
Janis IL:  Psychologic effects of electric convulsive treatments . J Nerv Ment Dis 3:359-382, 1950;.
Squire LR:  Remote memory as affected by aging . Neuropsychologia 12:429-435, 1974;.
Squire LR, Slater PC:  Anterograde and retrograde memory impairment in chronic amnesia . Neuropsychologia 16:313-322, 1978;.
Squire LR, Slater PC:  Forgetting in very long-term memory as assessed by an improved questionnaire technique . J Exp Psychol Hum Learn 104:50-54, 1975;.
Squire LR, Chace PM, Slater PC:  Assessment of memory for remote events . Psychol Rep 37:223-234, 1975;.
Janis IL, Astrachan M:  The effects of electroconvulsive treatments on memory efficiency . J Abnorm Soc Psychol 46:501-511, 1951;.
Winer BJ: Statistical Principles in Experimental Design . New York, McGraw-Hill Book Co, 1962;, p 198.
Squire LR:  Short-term memory as a biological entity , in Deutsch JA, Deutsch D (eds): Short-term Memory . New York, Academic Press Inc, 1975;, pp 1-40.
Sternberg DE, Jarvik ME:  Memory functions in depression: Improvement with antidepressant medication . Arch Gen Psychiatry 33:219-224, 1976;.
Cronholm B, Ottosson JO:  Memory functions in endogenous depression: Before and after electroconvulsive therapy . Arch Gen Psychiatry 5:193-199, 1961;.
Templer DI, Ruff CF, Armstrong GL:  Cognitive functioning and degree of psychosis in schizophrenics given many electroconvulsive treatments . Br J Psychiatry 123:441-443, 1973;.
Goldman H, Gomer FE, Templer DI:  Long-term effects of electroconvulsive therapy upon memory and perceptual-motor performance . J Clin Psychol 28:32-34, 1972;.
Strain J, Brunschwig L, Duffy JP, et al:  Comparison of therapeutic effects and memory changes with bilateral and unilateral ECT . Am J Psychiatry 125:50-60, 1968;.

First Page Preview

First page PDF preview

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Ilaria R, Prange AJ:  Convulsive therapy and other biological treatments , in Flack FF, Draghi SC (eds): The Nature and Treatment of Depression . New York, John Wiley & Sons Inc, 1975;, pp 271-308.
Turek IS, Hanlon TF:  The effectiveness and safety of electroconvulsive therapy (ECT) . J Nerv Ment Dis 164:419-431, 1977;.
Squire LR:  Electroconvulsive therapy and memory loss . Am J Psychiatry 134:997-1001, 1977;.
Harper RG, Wiens AN:  Electroconvulsive therapy and memory . J Nerv Ment Dis 161:245-254, 1975;.
Squire LR: Memory dysfunction and memory complaint: Long-term follow-up studies, in Autry J, Squire L, Cole J, et al (eds): ECT: Impact and Efficacy. New York, Spectrum Publications Inc, to be published.
Harper R: Anterograde amnesia: Acute effects of an average number of treatments, in Autry J, Squire L, Cole J, et al (eds): ECT: Impact and Efficacy. New York, Spectrum Publications Inc, to be published.
Squire LR, Slater PC:  Bilateral and unilateral ECT: Effects on verbal and nonverbal memory . Am J Psychiatry 135:1316-1320, 1978;.
Squire LR, Miller PL:  Diminution in anterograde amnesia following electroconvulsive therapy . Br J Psychiatry 125:490-495, 1974;.
Brunschwig L, Strain J, Bidder TG:  Issues in the assessment of post-ECT memory changes . Br J Psychiatry 119:73-74, 1971;.
Squire LR:  A stable impairment in remote memory following electroconvulsive therapy . Neuropsychologia 13:51-58, 1975;.
Bidder TG, Strain J, Brunschwig L:  Bilateral and unilateral ECT: Follow-up study and critique . Am J Psychiatry 127:737-745, 1970;.
Halliday AM, Davison K, Browne MW, et al:  A comparison of the effects on depression and memory of bilateral ECT and unilateral ECT to the dominant and nondominant hemispheres . Br J Psychiatry 114:997-1012, 1968;.
Squire LR, Chace PM:  Memory functions six to nine months after electroconvulsive therapy . Arch Gen Psychiatry 32:1557-1564, 1975;.
Russell WR, Nathan PW:  Traumatic amnesia . Brain 69:280-300, 1946;.
Squire LR, Slater PC, Chace PM:  Retrograde amnesia: Temporal gradient in very long-term memory following electroconvulsive therapy . Science 187:77-79, 1975;.
Squire LR, Chace PM, Slater PC:  Retrograde amnesia following electroconvulsive therapy . Nature 260:775-777, 1976;.
Squire LR, Cohen N:  Memory and amnesia: Resistance to disruption develops for years after learning . Behav Neural Biol 25:115-125, 1979;.
Janis IL:  Psychologic effects of electric convulsive treatments . J Nerv Ment Dis 3:359-382, 1950;.
Squire LR:  Remote memory as affected by aging . Neuropsychologia 12:429-435, 1974;.
Squire LR, Slater PC:  Anterograde and retrograde memory impairment in chronic amnesia . Neuropsychologia 16:313-322, 1978;.
Squire LR, Slater PC:  Forgetting in very long-term memory as assessed by an improved questionnaire technique . J Exp Psychol Hum Learn 104:50-54, 1975;.
Squire LR, Chace PM, Slater PC:  Assessment of memory for remote events . Psychol Rep 37:223-234, 1975;.
Janis IL, Astrachan M:  The effects of electroconvulsive treatments on memory efficiency . J Abnorm Soc Psychol 46:501-511, 1951;.
Winer BJ: Statistical Principles in Experimental Design . New York, McGraw-Hill Book Co, 1962;, p 198.
Squire LR:  Short-term memory as a biological entity , in Deutsch JA, Deutsch D (eds): Short-term Memory . New York, Academic Press Inc, 1975;, pp 1-40.
Sternberg DE, Jarvik ME:  Memory functions in depression: Improvement with antidepressant medication . Arch Gen Psychiatry 33:219-224, 1976;.
Cronholm B, Ottosson JO:  Memory functions in endogenous depression: Before and after electroconvulsive therapy . Arch Gen Psychiatry 5:193-199, 1961;.
Templer DI, Ruff CF, Armstrong GL:  Cognitive functioning and degree of psychosis in schizophrenics given many electroconvulsive treatments . Br J Psychiatry 123:441-443, 1973;.
Goldman H, Gomer FE, Templer DI:  Long-term effects of electroconvulsive therapy upon memory and perceptual-motor performance . J Clin Psychol 28:32-34, 1972;.
Strain J, Brunschwig L, Duffy JP, et al:  Comparison of therapeutic effects and memory changes with bilateral and unilateral ECT . Am J Psychiatry 125:50-60, 1968;.

Correspondence

CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Comment

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.