0
Article |

Interictal Electroencephalographic Effects of Electroconvulsive Therapy: Title and subTitle BreakCan They Elucidate Mechanism of Action?

Jan Volavka, MD, PhD; Pal Czobor, PhD
Arch Gen Psychiatry. 1996;53(9):826-827. doi:10.1001/archpsyc.1996.01830090074010
Text Size: A A A
Published online

ELECTROCONVULSIVE therapy (ECT) and electroencephalography (EEG) were developed within several years of each other in the early 1930s, and the effects of ECT on the ictal and interictal EEGs were reported soon thereafter. The EEG effects were massive and consistent; it seemed natural to view this EEG change as a concomitant, a precondition, or even an explanation of the clinical effects of ECT. These views were translated into hypotheses that were tested and presented in a large literature that goes back to the 1940s.

See also page 814  At least 3 domains have been studied in the literature involving interictal EEG: the treatment, the EEG, and the clinical outcome. The treatment variables include the position of the ECT electrodes, the stimulus intensity, and the number of treatments given at the time of the EEG. The EEG variables include the topographic distribution over the scalp (the number, location, and connections of

REFERENCES

Fink M, Kahn RL, Oaks G.  Relation of electroencephalographic delta activity to behavioral response in electroshock . Arch Neurol Psychiatry . 1957;;78:516-525.
Volavka J, Feldstein S, Abrams R, Dornbush R, Fink M.  EEG and clinical change after bilateral and unilateral electroconvulsive therapy . Electroencephalogr Clin Neurophysiol . 1972;;32:631-639.
Sackeim HA, Luber B, Katzman GP, Moeller JR, Prudic J, Devanand DP, Nobler MS.  The effects of electroconvulsive therapy on quantitative electroencephalograms; relationship to clinical outcome . Arch Gen Psychiatry . 1996;;53:814-824.
Alexander GE, Moeller JR.  Application of the Scaled Subprofile Model to functional imaging in neuropsychiatric disorders: a principal component approach to modeling brain function in disease . Human Brain Mapping . 1994;;2:79-94.
Gasser T, Mocks J, Bacher P.  Topographic factor analysis of the EEG with applications to development and to mental retardation . Electroencephalogr Clin Neurophysiol . 1983;;55:445-463.
Volkow ND, Gomez-Mont F, Inamdar S, Lamella M, Prichep L, John R.  Multivariate analyses of the EEG in normal adolescents . Biol Psychiatry . 1987;;22:199-204.
Michel CM, Lehmann D, Henggeler B, Brandeis D.  Localization of the sources of EEG delta, theta, alpha and beta frequency bands using the FFT dipole approximation . Electroencephalogr Clin Neurophysiol . 1992;;82:38-44.
Gevins A, Leong H, Smith ME, Le J, Du R.  Mapping cognitive brain function with modern highresolution electroencephalography . Trends Neurosci . 1995;;18:429-436.

First Page Preview

First page PDF preview

Figures

Tables

Interactive Graphics

Video

Country-Specific Mortality and Growth Failure in Infancy and Yound Children and Association With Material Stature

Use interactive graphics and maps to view and sort country-specific infant and early dhildhood mortality and growth failure data and their association with maternal

Fink M, Kahn RL, Oaks G.  Relation of electroencephalographic delta activity to behavioral response in electroshock . Arch Neurol Psychiatry . 1957;;78:516-525.
Volavka J, Feldstein S, Abrams R, Dornbush R, Fink M.  EEG and clinical change after bilateral and unilateral electroconvulsive therapy . Electroencephalogr Clin Neurophysiol . 1972;;32:631-639.
Sackeim HA, Luber B, Katzman GP, Moeller JR, Prudic J, Devanand DP, Nobler MS.  The effects of electroconvulsive therapy on quantitative electroencephalograms; relationship to clinical outcome . Arch Gen Psychiatry . 1996;;53:814-824.
Alexander GE, Moeller JR.  Application of the Scaled Subprofile Model to functional imaging in neuropsychiatric disorders: a principal component approach to modeling brain function in disease . Human Brain Mapping . 1994;;2:79-94.
Gasser T, Mocks J, Bacher P.  Topographic factor analysis of the EEG with applications to development and to mental retardation . Electroencephalogr Clin Neurophysiol . 1983;;55:445-463.
Volkow ND, Gomez-Mont F, Inamdar S, Lamella M, Prichep L, John R.  Multivariate analyses of the EEG in normal adolescents . Biol Psychiatry . 1987;;22:199-204.
Michel CM, Lehmann D, Henggeler B, Brandeis D.  Localization of the sources of EEG delta, theta, alpha and beta frequency bands using the FFT dipole approximation . Electroencephalogr Clin Neurophysiol . 1992;;82:38-44.
Gevins A, Leong H, Smith ME, Le J, Du R.  Mapping cognitive brain function with modern highresolution electroencephalography . Trends Neurosci . 1995;;18:429-436.

Correspondence

CME Course for:


You need to register in order to view this quiz.


To understand the clinical management of acute heart failure syndromes.
Accreditation Information The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
To view and print your certificate and access a summary of your CME courses go to My CME.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s “Cited By” API will populate this tab (http://www.crossref.org/citedby.html).
Submit a Response

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.