RT Journal A1 Kraemer HC T1 VAlidity and psychiatric diagnoses JF JAMA Psychiatry JO JAMA Psychiatry YR 2013 FD February 1 VO 70 IS 2 SP 138 OP 139 DO 10.1001/jamapsychiatry.2013.273 UL http://dx.doi.org/10.1001/jamapsychiatry.2013.273 AB The publication of DSM-5 looms, attracting criticism even in advance of field trial results or finalization of criteria. Such criticism may ultimately prove singularly productive in that DSM-5 proposes to become a living document. As soon as convincing evidence supports it, diagnostic modification could be implemented without waiting the traditional 15 to 20 years for the next DSM upheaval. Thus, critics are alerted that alternative proposals should be supported with evidence, not opinions. The DeFife et al study1 is a welcome harbinger of events to come, but is their evidence convincing? In general, what will it take to document validity of a proposed new diagnosis?