RT Journal
A1 Dunner DL
T1 LOng-term use of sedative and hypnotic medication
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 1999
FD April 1
VO 56
IS 4
SP 355
OP 355
DO 10.1001/archpsyc.56.4.355
UL http://dx.doi.org/10.1001/archpsyc.56.4.355
AB 
THE ARTICLE by Bunney et al1 is a partial report of the efficacy and safety of triazolam (Halcion; Upjohn Co, Kalamazoo, Mich) for use as a sedative and hypnotic medication. The report was requested by the Food and Drug Administration (FDA) task force to provide an independent assessment of the safety and efficacy of this compound. The 7 recommendations of this report suggest the need for more data, better integration of clinical trial and postmarketing surveillance data, increased attention to long-term clinical trials, and development of methods to assess long-term effects, in terms of efficacy, tolerance, and safety.