RT Journal
A1 Serretti A, Rietschel M, Lattuada E, et al
T1 FActor analysis of mania
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 1999
FD July 1
VO 56
IS 7
SP 671
OP 672
DO 10.1001/archpsyc.56.7.671
UL http://dx.doi.org/10.1001/archpsyc.56.7.671
AB 
As exact phenotype characterization is crucial for the identification of biological and genetic markers, the available diagnoses systems may be insufficient. In a recent article Cassidy et al3 describe the symptom structure of mania identifying dysphoria, psychomotor acceleration, psychosis, increased hedonic function, and irritable aggression as separate factors in a sample of 237 bipolar subjects. They point out the substantial lack of empirical studies supporting the psychopathological definition of manic states.4- 5 Therefore, a replication on a large sample is needed.