RT Journal
A1 Levin HS, McCauley SR, Josic C, et al
T1 PRedicting depression following mild traumatic brain injury
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 2005
FD May 1
VO 62
IS 5
SP 523
OP 528
DO 10.1001/archpsyc.62.5.523
UL http://dx.doi.org/10.1001/archpsyc.62.5.523
AB Context 
    Minimizing negative consequences of major depression following traumatic brain injury is an important public health objective. Identifying high-risk patients and referring them for treatment could reduce morbidity and loss of productivity.Objective 
    To develop a model for early screening of patients at risk for major depressive episode at 3 months after traumatic brain injury.Design 
    Prediction model using receiver operating characteristic curve.Setting 
    Level I trauma center in a major metropolitan area.Participants 
    Prospective cohort of 129 adults with mild traumatic brain injury.Main Outcome Measures 
    Center for Epidemiologic Studies Depression Scale score and current major depressive episode module of the Structured Clinical Interview for the DSM-IV.Results 
    A prediction model including higher 1-week Center for Epidemiologic Studies Depression Scale score, older age, and computed tomographic scans of intracranial lesions yielded 93% sensitivity and 62% specificity.Conclusion 
    This study supports the feasibility of identifying patients with mild traumatic brain injury who are at high risk for developing major depressive episode by 3 months’ postinjury, which could facilitate selective referral for potential treatment and reduction of negative outcomes.