RT Journal
T1 THis month in archives of general psychiatry
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 2006
FD June 1
VO 63
IS 6
SP 601
OP 601
DO 10.1001/archpsyc.63.6.601
UL http://dx.doi.org/10.1001/archpsyc.63.6.601
AB 
Corlett et alArticle report findings from ketamine-treated subjects, linking brain responses while taking placebo to the emergence of delusions at higher doses in the same subjects. The central findings, that frontal lobe responses to error-dependent associate learning are disrupted by ketamine and that delusional ideas are more likely to arise in subjects showing increased frontal sensitivity to such learning, suggest a link between frontal function, associate learning, and delusions.