RT Journal T1 THis month in archives of general psychiatry JF Archives of General Psychiatry JO Archives of General Psychiatry YR 2006 FD July 1 VO 63 IS 7 SP 714 OP 714 DO 10.1001/archpsyc.63.7.714 UL http://dx.doi.org/10.1001/archpsyc.63.7.714 AB Ho et alArticle found that the Met allele of a brain-derived neurotrophic factor, possibly through the factor's role in modulating synaptic plasticity, causes a specific cognitive dysfunction in schizophrenia. Unlike healthy volunteers, Met allele–carrier patients had greater visuospatial impairment and small gray matter brain volumes in both ventral and dorsal visual pathways than their Val-homozygous counterparts.