RT Journal T1 THis month in archives of general psychiatry JF Archives of General Psychiatry JO Archives of General Psychiatry YR 2009 FD June 1 VO 66 IS 6 SP 579 OP 579 DO 10.1001/archgenpsychiatry.2009.59 UL http://dx.doi.org/10.1001/archgenpsychiatry.2009.59 AB In a large sample of subjects with schizophrenia, McGrath et alArticle factor analyzed not only symptom and prodrome indicators but also indicators of function in child, adolescent, and adult periods. Nine factors covered traditional (hallucinations, negative, disorganized, affective, Schneiderian first-rank) as well as novel domains (scholastic, child/adolescent sociability, prodromal, and disability/impairment). Factor scores in all domains demonstrated significant familiality, offering a range of phenotypes for genetic analyses.