RT Journal T1 THis month in archives of general psychiatry JF Archives of General Psychiatry JO Archives of General Psychiatry YR 2009 FD October 1 VO 66 IS 10 SP 1043 OP 1043 DO 10.1001/archgenpsychiatry.2009.135 UL http://dx.doi.org/10.1001/archgenpsychiatry.2009.135 AB Donohoe et al (Article examined the effects on cognition of the NOS1 variant rs6490121, identified in a recent genome-wide association study as a potential schizophrenia risk variant. In large Irish samples, the risk genotype was found to be associated with clinically significant variation in both verbal IQ and working memory both in patients with schizophrenia and healthy participants. These findings were then replicated in large independent German samples of both patients and healthy participants.