RT Journal
T1 THis month in archives of general psychiatry
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 2009
FD December 1
VO 66
IS 12
SP 1285
OP 1285
DO 10.1001/archgenpsychiatry.2009.162
UL http://dx.doi.org/10.1001/archgenpsychiatry.2009.162
AB 
Meyer et alArticle used carbon 11–labeled harmine positron emission tomography to measure monoamine oxidase A (MAO-A) binding in different states of major depressive disorder (MDD). They found elevated MAO-A binding in affect-modulating brain regions during depressive episodes, during remission after selective serotonin reuptake inhibitor treatment, and during recovery. In subjects with MDD in recovery, greater MAO-A binding in the prefrontal and anterior cingulate cortex was associated with subsequent recurrence.