RT Journal
A1 Rich-Edwards J, Hacker M, Gillman M
T1 PRemature recommendation of corticotropin-releasing hormone as screen for postpartum depression
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 2009
FD August 1
VO 66
IS 8
SP 915
OP 917
DO 10.1001/archgenpsychiatry.2009.101
UL http://dx.doi.org/10.1001/archgenpsychiatry.2009.101
AB 
Yim and colleagues1 recently reported a positive association between maternal plasma levels of corticotropin-releasing hormone (CRH) at midpregnancy with risk of maternal depression at roughly 9 weeks postpartum. Their longitudinal cohort of 100 women yielded 16 cases of postpartum depression (PPD) at 9 weeks postpartum, as measured by the Edinburgh Postpartum Depression Scale with a threshold of 10 or greater to indicate probable minor depression. Yim and colleagues conclude that “midpregnancy pCRH [placental CRH] is a sensitive and specific early diagnostic test for PPD symptoms.’’1(p162)