RT Journal
A1 Leckman JF, Gershon ES, McGinniss MH, Targum SD, Dibble ED
T1 NEw data do not suggest linkage between the xg blood group and bipolar illness
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 1979
FD December 1
VO 36
IS 13
SP 1435
OP 1441
DO 10.1001/archpsyc.1979.01780130053006
UL http://dx.doi.org/10.1001/archpsyc.1979.01780130053006
AB • The Xg blood group antigen (a genetic marker of a region of the X chromosome at a considerable distance from protan/ deutan color blindness) was studied for linkage to bipolar manic-depressive illness. A multigenerational analytic method, taking variable penetrance into account, was used. In our series of six informative pedigrees, very close linkage could be definitively ruled out, and the likelihood of less tight linkage was consistently less than the likelihood of nonlinkage.