RT Journal A1 Kupfer DJ, Ulrich RF, Coble PA, et al T1 Electroencephalographic sleep of younger depressives: Comparison with normals JF Archives of General Psychiatry JO Archives of General Psychiatry YR 1985 FD August 1 VO 42 IS 8 SP 806 OP 810 DO 10.1001/archpsyc.1985.01790310068009 UL http://dx.doi.org/10.1001/archpsyc.1985.01790310068009 AB • The electroencephalographic sleep of younger depressives (aged 20 to 44 years) was compared with that of an age-matched group of normals. The patients demonstrated many of the typical sleep changes reported for older depressed populations: shortened rapid-eye-movement (REM) latency; REM sleep activity alterations, with a shift to the early portion of the night (first REM period); reduced delta sleep; and sleep efficiency reductions marked by sleep-onset difficulties. The traditional scoring procedures were supplemented by automated REM and delta-sleep analyses that provided more precise delineation of these differences between patients and normals, particularly the distributions of REM activity and delta-wave patterning.