RT Journal
A1 Frank E, Kupfer DJ, Perel JM
T1 EArly recurrence in unipolar depression
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 1989
FD May 1
VO 46
IS 5
SP 397
OP 400
DO 10.1001/archpsyc.1989.01810050011002
UL http://dx.doi.org/10.1001/archpsyc.1989.01810050011002
AB • While some advances have occurred in the maintenance treatment of unipolar depression, empirical data on recurrences of illness following the discontinuation of medication are sparse. We examined survival time during the first 18 months after discontinuation of medication in 74 patients with recurrent unipolar depression. Although demographic characteristics, clinical characteristics, and pharmacologic treatment variables failed to predict time to recurrence, continued interpersonal psychotherapy was significantly related to longer survival time.