RT Journal
A1 Shenton ME, Solovay MR, Holzman PS, Coleman M, Gale HJ
T1 THought disorder in the relatives of psychotic patients
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 1989
FD October 1
VO 46
IS 10
SP 897
OP 901
DO 10.1001/archpsyc.1989.01810100039007
UL http://dx.doi.org/10.1001/archpsyc.1989.01810100039007
AB • Using the Holzman-Johnston Thought Disorder Index, thought disorder was examined in the first-degree relatives of schizophrenic, manic, and schizoaffective patients. In all three groups, there was a tendency for probands with higher thought disorder to have first-degree relatives with higher thought disorder. Furthermore, the quality of thought disorder in the groups of relatives was similar to that in the groups of probands, although it was clear that the relatives of schizoaffective-manic patients showed the highest amount of thought disorder, which was not found in the proband sample. Although based on a small sample, these findings suggest that amount and type of thought disorder differ not only among medicated patient groups but also among their unmedicated relatives.