RT Journal
T1 THis month in archives of general psychiatry
JF Archives of General Psychiatry
JO Archives of General Psychiatry
YR 2006
FD August 1
VO 63
IS 8
SP 842
OP 842
DO 10.1001/archpsyc.63.8.842
UL http://dx.doi.org/10.1001/archpsyc.63.8.842
AB 
Gurling et alArticle report genetic association tests to pinpoint exactly which gene could be causing genetic susceptibility to schizophrenia within a chromosome 8 region previously showing linkage to schizophrenia. Magnetic resonance imaging of selected cases showed that PCM1-associated schizophrenia was significantly associated with reductions in the volume of the orbitofrontal cortex gray matter. Non-PCM1–associated schizophrenia was associated with reductions in the temporal lobe cortices, including the temporal pole, hippocampus, and inferior temporal cortex.