TY  - JOUR
T1  - INfluence of patient race and ethnicity on clinical assessment in patients with affective disorders
AU  - Gara MA, Vega WA, Arndt S, et al
Y1  - 2012/06/01
N1  - 10.1001/archgenpsychiatry.2011.2040
JO  - Archives of General Psychiatry
SP  - 593
EP  - 600
VL  - 69
IS  - 6
N2  - Context 
                  Rates of clinical diagnoses of schizophrenia in African American individuals appear to be elevated compared with other ethnic groups in the United States, contradicting population rates derived from epidemiologic surveys.Objective 
                  To determine whether African American individuals would continue to exhibit significantly higher rates of clinical diagnoses of schizophrenia, even after controlling for age, sex, income, site, and education, as well as the presence or absence of serious affective disorder, as determined by experts blinded to race and ethnicity. A secondary objective was to determine if a similar pattern occurred in Latino subjects.Design 
                  Ethnicity-blinded and -unblinded diagnostic assessments were obtained in 241 African American individuals (mean [SD] age, 34.3 [8.1] years; 57% women), 220 non-Latino white individuals (mean [SD] age, 32.7 [8.5] years; 53% women), and 149 Latino individuals (mean [SD] age, 33.5 [8.0] years; 58% women) at 6 US sites. Logistic regression models were used to determine whether elevated rates of schizophrenia in African American individuals would persist after controlling for various confounding variables including blinded expert consensus diagnoses of serious affective illness.Settings 
                  Six academic medical centers across the United States.Participants 
                  Six hundred ten psychiatric inpatients and outpatients.Main Outcome Measure 
                  Relative odds of unblinded clinical diagnoses of schizophrenia in African American compared with white individuals.Results 
                  A significant ethnicity/race effect (χ22 = 10.4, P = .01) was obtained when schizophrenia was narrowly defined, controlling for all other predictors. The odds ratio comparing African American with non-Latino white individuals was significant (odds ratio = 2.7; 95% CI, 1.5-5.1). Similar differences between African American and white individuals occurred when schizophrenia was more broadly defined (odds ratio = 2.5; 95% CI, 1.4-4.5). African American individuals did not differ significantly from white individuals in overall severity of manic and depressive symptoms but did evidence more severe psychosis.Conclusions 
                  African American individuals exhibited significantly higher rates of clinical diagnoses of schizophrenia than non-Latino white subjects, even after controlling for covariates such as serious affective disorder.
SN  - 0003-990X
M3  - doi: 10.1001/archgenpsychiatry.2011.2040
UR  - http://dx.doi.org/10.1001/archgenpsychiatry.2011.2040
ER  -