TY  - JOUR
T1  - WHat conditions are necessary to assess antidepressant efficacy?
AU  - Quitkin FM, Klein DF
Y1  - 2000/04/01
N1  - 10.1001/archpsyc.57.4.323
JO  - Archives of General Psychiatry
SP  - 323
EP  - 324
VL  - 57
IS  - 4
N2  - 
We believe that these data can appropriately assess morbidity but do not adequately assess efficacy. The only data available were pretreatment and posttreatment mean total Hamilton Depression Rating scores, most without SEs. Although constrained by database inadequacies, effect size estimates were calculated and Khan et al report that "nearly half the studies had less than medium effect size (<0.5)."

SN  - 0003-990X
M3  - doi: 10.1001/archpsyc.57.4.323
UR  - http://dx.doi.org/10.1001/archpsyc.57.4.323
ER  -