TY - JOUR T1 - The interplay of nature, nurture, and developmental influences: The challenge ahead for mental health AU - Rutter M Y1 - 2002/11/01 N1 - 10.1001/archpsyc.59.11.996 JO - Archives of General Psychiatry SP - 996 EP - 000 VL - 59 IS - 11 N2 - This article succinctly reviews research achievements in the fields of psychiatric genetics, psychosocial influences on mental disorder, and developmental processes. The challenges for the future are discussed in relation to finding and understanding the following: (1) susceptibility genes; (2) environmentally mediated causal risk processes; (3) nature-nurture interplay; (4) the effects of psychosocial adversity on the organism; (5) the causal processes responsible for group differences in rates of disorder; and (6) age-related changes in psychopathological characteristics. SN - 0003-990X M3 - doi: 10.1001/archpsyc.59.11.996 UR - http://dx.doi.org/10.1001/archpsyc.59.11.996 ER -