TY  - JOUR
T1  - ASsociation between obesity and psychiatric disorders in the us adult population
AU  - Simon GE, Von Korff M, Saunders K, et al
Y1  - 2006/07/01
N1  - 10.1001/archpsyc.63.7.824
JO  - Archives of General Psychiatry
SP  - 824
EP  - 830
VL  - 63
IS  - 7
N2  - Background 
    Epidemiologic data suggest an association between obesity and depression, but findings vary across studies and suggest a stronger relationship in women than men.Objective 
    To evaluate the relationship between obesity and a range of mood, anxiety, and substance use disorders in the US general population.Design 
    Cross-sectional epidemiologic survey.Setting 
    Nationally representative sample of US adults.Participants 
    A total of 9125 respondents who provided complete data on psychiatric disorder, height, and weight. Response rate was 70.9%.Main Outcome Measures 
    Participants completed an in-person interview, including assessment of a range of mental disorders (assessed using the World Health Organization Composite International Diagnostic Interview) and height and weight (by self-report).Results 
    Obesity (defined as body mass index [calculated as weight in kilograms divided by the square of height in meters] of ≥30) was associated with significant increases in lifetime diagnosis of major depression (odds ratio [OR], 1.21; 95% confidence interval [CI], 1.09-1.35), bipolar disorder (OR, 1.47; 95% CI, 1.12-1.93), and panic disorder or agoraphobia (OR, 1.27; 95% CI, 1.01-1.60). Obesity was associated with significantly lower lifetime risk of substance use disorder (OR, 0.78; 95% CI, 0.65-0.93). Subgroup analyses found no difference in these associations between men and women, but the association between obesity and mood disorder was strongest in non-Hispanic whites (OR, 1.38; 95% CI, 1.20-1.59) and college graduates (OR, 1.44; 95% CI, 1.14-1.81).Conclusions 
    Obesity is associated with an approximately 25% increase in odds of mood and anxiety disorders and an approximately 25% decrease in odds of substance use disorders. Variation across demographic groups suggests that social or cultural factors may moderate or mediate the association between obesity and mood disorder.
SN  - 0003-990X
M3  - doi: 10.1001/archpsyc.63.7.824
UR  - http://dx.doi.org/10.1001/archpsyc.63.7.824
ER  -