TY - JOUR T1 - SCientific and ethical issues related to deep brain stimulation for disorders of mood, behavior, and thought AU - Rabins P, Appleby BS, Brandt J, et al Y1 - 2009/09/01 N1 - 10.1001/archgenpsychiatry.2009.113 JO - Archives of General Psychiatry SP - 931 EP - 937 VL - 66 IS - 9 N2 - Context  A 2-day consensus conference was held to examine scientific and ethical issues in the application of deep brain stimulation for treating mood and behavioral disorders, such as major depression, obsessive-compulsive disorder, and Tourette syndrome.Objectives  The primary objectives of the conference were to (1) establish consensus among participants about the design of future clinical trials of deep brain stimulation for disorders of mood, behavior, and thought and (2) develop standards for the protection of human subjects participating in such studies.Results  Conference participants identified 16 key points for guiding research in this growing field.Conclusions  The adoption of the described guidelines would help to protect the safety and rights of research subjects who participate in clinical trials of deep brain stimulation for disorders of mood, behavior, and thought and have further potential to benefit other stakeholders in the research process, including clinical researchers and device manufactures. That said, the adoption of the guidelines will require broad and substantial commitment from many of these same stakeholders. SN - 0003-990X M3 - doi: 10.1001/archgenpsychiatry.2009.113 UR - http://dx.doi.org/10.1001/archgenpsychiatry.2009.113 ER -