TY - JOUR T1 - STage 4 sleep in schizophrenia AU - Feinberg I, Braun MM, Koresko RL, Gottlieb FF Y1 - 1969/09/01 N1 - 10.1001/archpsyc.1969.01740210006002 JO - Archives of General Psychiatry SP - 262 EP - 266 VL - 21 IS - 3 N2 - THE stage 4 EEG (employing the Dement and Kleitman1 nomenclature) of sleep, as measured in our laboratory, consists of high-voltage (over 50V) slow (under 4 cycles per second) activity occurring with a stipulated density (over 16 waves per 20second epoch, or over 50% of the epoch occupied by such slow waves). Stage 3 EEG represents a lesser density (10 to 16 waves per 20-second epoch) of this slow-wave activity. Stage 3 and 4 EEG constitute, along with spindles and K-complexes, the distinguishing features of nonrapid eye-movement (NREM) or slow-wave sleep. Both stage 3 and 4 EEG are maximal during the first few hours of sleep1 and their distributions across the night may usefully be described as a function of the successive sleep cycles.2Stage 4 EEG reaches its highest level in early childhood3 and then shows a hyper SN - 0003-990X M3 - doi: 10.1001/archpsyc.1969.01740210006002 UR - http://dx.doi.org/10.1001/archpsyc.1969.01740210006002 ER -