TY  - JOUR
T1  - REduction of cigarette smoking by use of a nicotine patch
AU  - Hartman N, Jarvik ME, Wilkins JN
Y1  - 1989/03/01
N1  - 10.1001/archpsyc.1989.01810030095014
JO  - Archives of General Psychiatry
SP  - 289
EP  - 289
VL  - 46
IS  - 3
N2  - To the Editor.— 
    A pilot study that suggests that cigarette smoking by hospitalized psychiatric patients can be reduced through the use of a transdermal nicotine patch was performed at the Treatment Refractory Unit of the Veterans Administration Medical Center West Los Angeles.Subjects and Methods.— 
    Three moderate smokers (one to two packs per day for at least ten years) gave informed consent for participation in the following single-blind study. In two separate seven-hour procedures, one week apart, 24 μL of either a solution containing 30% nicotine base or water (the control) was applied to the nondominant forearm and covered by a 3-cm-square patch of polyethylene wrap, secured at the edges by surgical tape. This type of patch was used in a previous study of nicotine titration using a smoke-mixing apparatus.1The solutions were administered at 9 AM, and patients were provided with unlimited access to a standard popular
SN  - 0003-990X
M3  - doi: 10.1001/archpsyc.1989.01810030095014
UR  - http://dx.doi.org/10.1001/archpsyc.1989.01810030095014
ER  -