TY - JOUR T1 - The pendulum swings the other way: The role of environment obscured by genes-reply AU - Buydens-Branchey L, Branchey MH Y1 - 1989/12/01 N1 - 10.1001/archpsyc.1989.01810120093015 JO - Archives of General Psychiatry SP - 1151 EP - 1152 VL - 46 IS - 12 N2 - In Reply.—  We would like to clarify some of the points raised by Dr Vaillant. In the first of our two articles we reviewed the various classification schemes proposed in the literature for the subdivision of alcoholics into relatively homogeneous subgroups. In particular, we reviewed the work of Cloninger, who, on the basis of adoption studies, provided evidence for the existence of two forms of inherited alcoholism in men.It will be remembered that one form, present in a subgroup of patients classified as type 2, was found to be highly heritable and independent of environmental influences. Type 2 patients were observed to exhibit alcohol-seeking behavior early in life, to be impulsive and risk taking, and to have a tendency to manifest antisocial behavior. The other form of inherited alcoholism, type 1, was found to necessitate a postnatal provocation in addition to the genetic predisposition if a susceptibility to alcoholism was SN - 0003-990X M3 - doi: 10.1001/archpsyc.1989.01810120093015 UR - http://dx.doi.org/10.1001/archpsyc.1989.01810120093015 ER -