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Basic View | Expanded View
 Showing 1-20 of 32 Articles
Viewpoint 
Susan M. Essock, PhD

This Viewpoint reflects on actions patients, clinicians, and payers may consider when a managed behavioral health care organization refuses particular care.

Original Investigation  FREE
Charlotte Wessel Skovlund, MSc; Lina Steinrud Mørch, PhD; Lars Vedel Kessing, MD, DMSc; Øjvind Lidegaard, MD, DMSc
Includes: Supplemental Content

Importance  Millions of women worldwide use hormonal contraception. Despite the clinical evidence of an influence of hormonal contraception on some women’s mood, associations between the use of hormonal contraception and mood disturbances remain inadequately addressed.

Objective  To investigate whether the use of hormonal contraception is positively ...

Original Investigation  FREE
Tabea Schoeler, MSc; Natalia Petros, MSc; Marta Di Forti, PhD; Jean-Baptiste Pingault, PhD; Ewa Klamerus, BSc; Enrico Foglia, BSc; Amanda Small, BSc; Robin Murray, FRS; Sagnik Bhattacharyya, PhD
Includes: Supplemental Content

Importance  Cannabis use after first-episode psychosis is associated with poor outcomes, but the causal nature of this association is unclear.

Objective  To examine the precise nature of the association between continued cannabis use after the onset of psychosis and risk of relapse of psychosis.

Design, Setting, ...

Editorial 
Merete Nordentoft, DMSc; Annette Erlangsen, PhD; Trine Madsen, PhD

It is devastating when a person who has recently been discharged from a psychiatric hospital dies by suicide. The act demonstrates the patient’s suffering, lack of hope, disappointment, and despair. Family members and next of kin are hit by sorrow and crisis. Often they will blame themselves or ...

Topics: suicide; nightmare
Original Investigation 
Mark Olfson, MD, MPH; Melanie Wall, PhD; Shuai Wang, PhD; Stephen Crystal, PhD; Shang-Min Liu, MS; Tobias Gerhard, PhD; Carlos Blanco, MD, PhD
Includes: Supplemental Content

Importance  Although psychiatric inpatients are recognized to be at increased risk for suicide immediately after hospital discharge, little is known about the extent to which their short-term suicide risk varies across groups with major psychiatric disorders.

Objective  To describe the risk for suicide during the 90 ...

Editorial: Postdischarge Suicides; Merete Nordentoft, DMSc; Annette Erlangsen, PhD; Trine Madsen, PhD
Neuroscience and Psychiatry 
Tobias U. Hauser, PhD; Eran Eldar, PhD; Raymond J. Dolan, FRS, MD

This article analyzes the mechanisms of harm-avoidance learning as a potential model for obsessive-compulsive disorder.

Research Letter 
Woojae Myung, MD; Hong Choi, MD, PhD; Chunsoo Lee, MD; Jun Ro Lee, MD; Bernard J. Carroll, MBBS, PhD, FRCPsych; Doh Kwan Kim, MD, PhD

This study discusses the association between levels of high-sensitivity C-reactive protein and general psychological distress symptoms.

Editorial 
Manuel J. Cuesta, MD, PhD; Victor Peralta, MD, PhD

The symptoms of schizophrenia span a wide range of psychopathology and display an extraordinary amount of interindividual and temporal variability. Over time, authors have invested different diagnostic value to symptoms, depending on their theoretical point of view. For Emil Kraepelin, dementia praecox was a nosological entity and the ...

Topics: schizophrenia
Original Investigation 
James C. Garbutt, MD; Alexey B. Kampov-Polevoy, MD, PhD; Linda S. Kalka-Juhl, MEd; Robert J. Gallop, PhD
Includes: Supplemental Content

Importance  Identification of moderators of the response to naltrexone hydrochloride treatment for alcohol dependence could improve clinical care for patients with alcohol use disorders.

Objective  To investigate the preliminary finding that the sweet-liking (SL) phenotype interacts with a high level of craving for alcohol and is ...

Original Investigation 
Thomas H. McCoy Jr, MD; Victor M. Castro, MS; Ashlee M. Roberson, BA; Leslie A. Snapper, BS; Roy H. Perlis, MD, MS
Includes: Supplemental Content

Importance  Suicide represents the 10th leading cause of death across age groups in the United States (12.6 cases per 100 000) and remains challenging to predict. While many individuals who die by suicide are seen by physicians before their attempt, they may not seek psychiatric care.

Objective  ...

Original Investigation 
Ricardo E. Jorge, MD; Laura Acion, PhD; Debora I. Burin, PhD; Robert G. Robinson, MD
Includes: Supplemental Content

Importance  Prevention is more effective than treatment to decrease the burden of significant medical conditions such as depressive disorders, a major cause of disability worldwide. Traumatic brain injury (TBI) is a candidate for selective strategies to prevent depression given the incidence, prevalence, and functional effect of depression ...

Special Communication 
Kenneth S. Kendler, MD

Importance  This article aims to determine the degree to which modern operationalized diagnostic criteria for schizophrenia reflect the main clinical features of the disorder as described historically by diagnostic experts.

Observations  Amazon.com, the National Library of Medicine, and Forgottenbooks.com were searched for articles written or translated ...

Editorial: Going Beyond Classic Descriptions of Schizophrenia; Manuel J. Cuesta, MD, PhD; Victor Peralta, MD, PhD
Comment & Response 
Michael Berk, MD, PhD; Susannah Tye, PhD; Ken Walder, PhD; Sean McGee, PhD

To the Editor In their article in JAMA Psychiatry, Janssen and colleagues1 describe an intriguing pilot study showing that whole-body hyperthermia was superior to sham in reducing depression. Their conjecture was that warm-sensitive afferent thermosensory pathways affect mood regulatory neural activity.1 However, these data support ...

Comment & Response 
Max Fink, MD; Edward Shorter, PhD

To the Editor The study by Janssen et al1 of a single exposure to whole-body hyperthermia relieving major depressive disorder is difficult to interpret and will need replication. The participants were highly selected from among long-time ill individuals with modest scores on the 17-item Hamilton Depression Rating ...

Comment & Response 
Charles L. Raison, MD; Clemens W. Janssen, PhD; Christopher A. Lowry, PhD

In Reply We appreciate the insightful observations and questions raised by the letters from Fink and Shorter and Berk et al regarding our article.1 Here, we respond to each letter in turn.

Editorial 
Craig S. Anderson, MD, PhD

Funders and leaders of health and social services are increasingly seeking evidence-based solutions to help address demands brought about by demographic shifts, high prevalence of chronic diseases, and economic constraints affecting populations and systems of care. Reliable data on the efficacy and cost-effectiveness of therapies and treatment strategies ...

Editorial 
Carlos Blanco, MD, PhD; Wilson M. Compton, MD, MPE; Bridget F. Grant, PhD, PhD

Despite our increased understanding of their neurobiology and social determinants, the treatment of psychiatric disorders continues to be a major public health problem. A better understanding of their natural history could advance our comprehension of their etiology and inform efforts to develop more effective treatment and preventive interventions. ...

Editorial 
Xuan Li, PhD; Marco Venniro, PhD; Yavin Shaham, PhD

In 1986, Gawin and Kleber1 proposed that cue-induced cocaine craving increases progressively during early abstinence and remains high during extended periods. However, subsequent inpatient clinical studies in the late 1980s have shown that baseline (nonprovoked) craving for cocaine decreases progressively during the first month of abstinence.2...

Original Investigation 
Diana Paksarian, PhD; Lihong Cui, MS; Jules Angst, MD; Vladeta Ajdacic-Gross, PhD; Wulf Rössler, MD; Kathleen R. Merikangas, PhD
Includes: Supplemental Content

Importance  Epidemiologic evidence indicates that most of the general population will experience a mental health disorder at some point in their lives. However, few prospective population-based studies have estimated trajectories of risk for mental disorders from young through middle adulthood to estimate the proportion of individuals who ...

Editorial: Toward Precision Epidemiology; Carlos Blanco, MD, PhD; Wilson M. Compton, MD, MPE; Bridget F. Grant, PhD, PhD
Original Investigation 
Terese S. H. Jørgensen, MSc; Ida K. Wium-Andersen, MD; Marie K. Wium-Andersen, MD, PhD; Martin B. Jørgensen, MD, DMSc; Eva Prescott, MD, DMSc; Solvej Maartensson, MSc, PhD; Per Kragh-Andersen, MSc, DMSc; Merete Osler, MD, DMSc, PhD
Includes: Supplemental Content

Importance  More than 30 million people live with a stroke diagnosis worldwide. Depression after stroke is frequent, and greater knowledge of associated risk factors and outcomes is needed to understand the etiology and implications of this disabling complication.

Objectives  To examine whether the incidence of and ...

Editorial: Depression After Stroke; Craig S. Anderson, MD, PhD

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