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  • JAMA Psychiatry February 1, 2017

    Figure 2: Anxiety, Self-esteem, and Life Satisfaction Trajectories After Seeking Abortion

    A, Anxiety symptoms in the previous 7 days as measured by the Brief Symptom Inventory. B, Cases of anxiety as measured by the Brief Symptom Inventory among participants since they sought an abortion. C, High self-esteem in the previous 7 days. 5 indicates extremely high; 3, moderately high; and 1, not at all. D, Satisfaction with life in the previous 7 days. 5 indicates extremely high; 3, moderately high; and 1, not at all.
  • Women’s Mental Health and Well-being 5 Years After Receiving or Being Denied an Abortion: A Prospective, Longitudinal Cohort Study

    Abstract Full Text
    JAMA Psychiatry. 2017; 74(2):169-178. doi: 10.1001/jamapsychiatry.2016.3478

    This longitudinal cohort study uses data from the Turnaway Study to women’s psychological well-being 5 years after receiving or being denied an abortion.

  • JAMA Psychiatry February 1, 2012

    Figure: First-Time First-Trimester Induced Abortion and Risk of Readmission to a Psychiatric Hospital in Women With a History of Treated Mental Disorder

    Figure 1. Crude incidence rates per 100 person-years of readmission among women with records of preexisting mental disorders who have had first-time first-trimester induced abortions or given birth.
  • First-Time First-Trimester Induced Abortion and Risk of Readmission to a Psychiatric Hospital in Women With a History of Treated Mental Disorder

    Abstract Full Text
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    Arch Gen Psychiatry. 2012; 69(2):159-165. doi: 10.1001/archgenpsychiatry.2011.153
  • Psychological Responses of Women After First-Trimester Abortion

    Abstract Full Text
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    Arch Gen Psychiatry. 2000; 57(8):777-784. doi: 10.1001/archpsyc.57.8.777
  • Abortion and the Null Hypothesis

    Abstract Full Text
    Arch Gen Psychiatry. 2000; 57(8):785-786. doi: 10.1001/archpsyc.57.8.785
  • JAMA Psychiatry February 1, 2012

    Figure: First-Time First-Trimester Induced Abortion and Risk of Readmission to a Psychiatric Hospital in Women With a History of Treated Mental Disorder

    Figure 2. Fully adjusted relative risk of readmission. A, Readmission risk before and after first-time first-trimester induced abortions in women with 1 or more previous admissions. Adjusted for age, calendar period, previous diagnoses, number of previous admissions, time since previous discharge, family history of mental disorders, and parental status. Readmission risk from 9 months before the abortion to 12 months after the abortion is shown; the reference category is risk of readmission in women having an abortion 11 to 12 months earlier. Limit lines indicate 95% CIs. B, Readmission risk before and after birth of live-born child in women with 1 or more previous admissions. Adjusted for age, calendar period, previous diagnoses, number of previous admission, time since previous discharge, family history of mental disorders, and abortion status. Readmission risk from 9 months before giving birth to 12 months after giving birth is shown; the reference category is risk of readmission in women giving birth 11 to 12 months earlier. Limit lines indicate 95% confidence intervals.
  • Association of Maternal Exposure to Childhood Abuse With Elevated Risk for Autism in Offspring

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    JAMA Psychiatry. 2013; 70(5):508-515. doi: 10.1001/jamapsychiatry.2013.447
    Roberts et al assessed whether maternal exposure to childhood abuse and adverse perinatal circumstances among abused women are associated with autism risk in offspring. Using data from the Nurses’ Health Study II, the prevalence of autism spectrum disorder was assessed. Controls were children of women who did not report autism in offspring.
  • Selected Pregnancy and Delivery Outcomes After Exposure to Antidepressant Medication: A Systematic Review and Meta-analysis

    Abstract Full Text
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    JAMA Psychiatry. 2013; 70(4):436-443. doi: 10.1001/jamapsychiatry.2013.684
    Ross et al performed a meta-analysis of 23 studies evaluating the use of antidepressants in pregnancy.
  • Neonatal Outcomes in Women With Untreated Antenatal Depression Compared With Women Without Depression: A Systematic Review and Meta-analysis

    Abstract Full Text
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    JAMA Psychiatry. 2016; 73(8):826-837. doi: 10.1001/jamapsychiatry.2016.0934

    This meta-analysis of randomized and observational studies reports comparison of neonatal outcomes among women with untreated antenatal depression vs no depression.

  • JAMA Psychiatry January 1, 2016

    Figure 1: Distribution of IQ Measures in BP4-BP5 16p11.2 Duplication and Deletion Carriers and Intrafamilial Noncarrier Control Individuals

    A-C, Box plots. Bold line indicates median; circles, outliers; dot inside the box, mean; top of each box, the 75th percentile (Q3); bottom of each box, 25th percentile (Q1); upper end of the error bar, the highest observed data value within the span from Q3 to Q3 + 1.5 times the interquartile range (IQR) (calculated as Q3 – Q1); the lower end, the lowest observed data value within the span from Q1 to Q1 – 1.5 times the IQR; shading, intellectual disability range (IQ ≤ 70); and dotted line, population mean (IQ = 100). The numbers below the graphs represent the number of duplication and deletion carriers in each group. D and E, Density plots. Increased variance is seen in the duplication group with a significant excess of low- and high-functioning duplication carriers compared with the deletion group, which was ascertained with the same method. The Full-Scale IQ (FSIQ) of probands with autism spectrum disorder (ASD) is significantly lower in duplication compared with deletion carriers.aP < .05.bP < .1.
  • Association of Age at Menopause and Duration of Reproductive Period With Depression After Menopause: A Systematic Review and Meta-analysis

    Abstract Full Text
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    JAMA Psychiatry. 2016; 73(2):139-149. doi: 10.1001/jamapsychiatry.2015.2653

    This meta-analysis of observational studies investigates associations between age at menopause, duration of the reproductive period, and depression in postmenopausal women.

  • JAMA Psychiatry August 1, 2015

    Figure 1: Polymerase Chain Reaction Determination of Relative Messenger RNA (mRNA) Levels for NARP, ARC, and SGK1 in Schizophrenia and Healthy Control Samples

    NARP mRNA is expressed in pyramidal cells (P), and NARP protein is secreted at excitatory synapses on the dendrites of parvalbumin interneurons (PV) (A). At these synapses, NARP contributes to the clustering of AMPA receptors. The levels of NARP (B), ARC (D), and SGK1 (E) mRNA for each control and schizophrenia sample in a pair. Data points below the diagonal unity line indicate lower mRNA levels in the schizophrenia sample relative to its matched control and vice versa. B, Mean NARP mRNA level was significantly lower in schizophrenia samples relative to matched controls. C, NARP mRNA levels were positively correlated with GAD67 mRNA levels in schizophrenia samples (black line) but not in controls (gray line). D and E, Mean levels of ARC and SGK1 mRNA did not differ significantly between groups.
  • Orbitofrontal Cortex and Drug Use During Adolescence: Role of Prenatal Exposure to Maternal Smoking and BDNF Genotype

    Abstract Full Text
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    Arch Gen Psychiatry. 2009; 66(11):1244-1252. doi: 10.1001/archgenpsychiatry.2009.124
  • Perinatal Factors and the Development of Autism: A Population Study

    Abstract Full Text
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    Arch Gen Psychiatry. 2004; 61(6):618-627. doi: 10.1001/archpsyc.61.6.618
  • Chronic Anxiety Treated by Feedback-Induced Muscle Relaxation: A Pilot Study

    Abstract Full Text
    Arch Gen Psychiatry. 1973; 28(2):263-267. doi: 10.1001/archpsyc.1973.01750320091014
  • JAMA Psychiatry November 1, 2010

    Figure 4: Relationship Between Amygdala Responses to Masked Faces and Mood State and Treatment in Major Depressive Disorder

    Neuroimaging results for experiment 3. A through C, Areas in the amygdala where the hemodynamic response to masked sad vs masked neutral (SN-NN) and masked happy vs masked neutral (HN-NN) faces differed in patients with major depressive disorder (MDD) after sertraline hydrochloride treatment vs the pretreatment baseline. β-weights are shown for specified contrasts for identified loci (A). D and E, Location in the right amygdala shows a time × group interaction. β-weights are shown for the specified contrasts as obtained during the 2 functional magnetic resonance imaging time points for the healthy controls (HCs) and MDD groups. dMDD indicates currently depressed people with MDD; dMDD-pre, dMDD before treatment.
  • Cocaine Vaccine for the Treatment of Cocaine Dependence in Methadone-Maintained Patients: A Randomized, Double-blind, Placebo-Controlled Efficacy Trial

    Abstract Full Text
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    Arch Gen Psychiatry. 2009; 66(10):1116-1123. doi: 10.1001/archgenpsychiatry.2009.128
  • JAMA Psychiatry March 1, 2009

    Figure 1: Common and Distinct Amygdala-Function Perturbations in Depressed vs Anxious Adolescents

    Amygdala activation to fearful faces in patients with anxiety and major depressive disorder (MDD) relative to healthy controls for select attention conditions. A, Left amygdala activation to fearful faces relative to fixation (error bars reflect standard errors) displaying the group (healthy controls, MDD with and without anxiety disorder, anxiety disorder alone) × attention condition interaction. A similar activation pattern was found for the right amygdala and when patients with comorbid MDD/anxiety were excluded (not shown). B and C, Left amygdala activation to fearful faces during afraid ratings vs passive viewing (“fearful-afraid vs fearful-passive” contrast) showing significantly enhanced activation among both anxiety and MDD groups compared with healthy controls, with no difference between patients with anxiety and patients with MDD. D and E, The fearful-afraid vs fearful-passive contrast evidences significantly greater left amygdala activation in patients with anxiety alone than in controls (D) (Montreal Neurological Institute [MNI] coordinates: −20, −2, −20, P = .001 (shown in figure); −10, −4, −16, P = .002; MNI coordinates are small-volume corrected) and in patients with MDD alone than in controls (E) (MNI coordinates: −20, 4, −16, P = .007; small-volume corrected). Highlighted areas indicate regions where the differences in blood oxygen level–dependent activation between groups were significant (for display purposes, uncorrected threshold was set at P = .0005 [D] and P = .005 [E]).